TY - GEN AU - Lan,K K AU - DeMets,D L TI - Changing frequency of interim analysis in sequential monitoring SN - 0006-341X PY - 1989///1113 KW - Biometry KW - Clinical Trials as Topic KW - methods KW - Humans KW - Models, Statistical KW - Probability N1 - Publication Type: Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S ER -