Vazquez, Michael L <br/><br/>
Identification of N-propane-1-sulfonamide (PF-04965842): A Selective JAK1 Clinical Candidate for the Treatment of Autoimmune Diseases.  [electronic resource] 

 -  Journal of medicinal chemistry  02 2018 
 - 1130-1152 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1520-4804 
<br/><br/><label>Standard No.: </label>10.1021/acs.jmedchem.7b01598  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Arthritis, Experimental--drug therapy<br/>Autoimmune Diseases--drug therapy<br/>Cyclobutanes--chemistry<br/>Dogs<br/>Drug Evaluation, Preclinical<br/>Humans<br/>Inhibitory Concentration 50<br/>Janus Kinase 1--antagonists & inhibitors<br/>Janus Kinase 2--antagonists & inhibitors<br/>Models, Molecular<br/>Protein Conformation<br/>Protein Kinase Inhibitors--chemistry<br/>Pyrimidines--chemistry<br/>Pyrroles--chemistry<br/>Rats<br/>Substrate Specificity<br/>Sulfonamides--chemistry<br/>Tissue Distribution