PrLZ increases prostate cancer docetaxel resistance by inhibiting LKB1/AMPK-mediated autophagy. [electronic resource]
- Theranostics 2018
- 109-123 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1838-7640
10.7150/thno.20356 doi
AMP-Activated Protein Kinase Kinases AMP-Activated Protein Kinases--genetics Animals Apoptosis--drug effects Autophagy--drug effects Cell Line, Tumor Cell Proliferation--drug effects Docetaxel Flow Cytometry Humans Immunohistochemistry Immunoprecipitation Male Mice Mice, Nude Neoplasm Proteins--genetics Prostatic Neoplasms--drug therapy Protein Serine-Threonine Kinases--genetics Real-Time Polymerase Chain Reaction Signal Transduction--drug effects Taxoids--therapeutic use