Clarke, Earl

Design and synthesis of a potent, highly selective, orally bioavailable, retinoic acid receptor alpha agonist. [electronic resource] - Bioorganic & medicinal chemistry 02 2018 - 798-814 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1464-3391

10.1016/j.bmc.2017.12.015 doi


Administration, Oral
Aminobenzoates--chemistry
Animals
Benzoates--chemistry
COS Cells
Cell Survival--drug effects
Chlorocebus aethiops
Drug Design
Half-Life
Hep G2 Cells
Humans
Mice
Microsomes, Liver--metabolism
Rats
Receptors, Retinoic Acid--agonists
Retinoic Acid Receptor alpha--agonists
Structure-Activity Relationship
Tetrahydronaphthalenes--chemistry
Retinoic Acid Receptor gamma