Clarke, Earl
Design and synthesis of a potent, highly selective, orally bioavailable, retinoic acid receptor alpha agonist. [electronic resource]
- Bioorganic & medicinal chemistry 02 2018
- 798-814 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1464-3391
10.1016/j.bmc.2017.12.015 doi
Administration, Oral
Aminobenzoates--chemistry
Animals
Benzoates--chemistry
COS Cells
Cell Survival--drug effects
Chlorocebus aethiops
Drug Design
Half-Life
Hep G2 Cells
Humans
Mice
Microsomes, Liver--metabolism
Rats
Receptors, Retinoic Acid--agonists
Retinoic Acid Receptor alpha--agonists
Structure-Activity Relationship
Tetrahydronaphthalenes--chemistry
Retinoic Acid Receptor gamma