Xu, Shilin <br/><br/>
Design of the First-in-Class, Highly Potent Irreversible Inhibitor Targeting the Menin-MLL Protein-Protein Interaction.  [electronic resource] 

 -  Angewandte Chemie (International ed. in English)  02 2018 
 - 1601-1605 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S. 
<br/><br/><label>ISSN: </label>1521-3773 
<br/><br/><label>Standard No.: </label>10.1002/anie.201711828  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Antineoplastic Agents--chemistry<br/>Binding Sites<br/>Cell Line, Tumor<br/>Cell Proliferation--drug effects<br/>Crystallography, X-Ray<br/>Drug Design<br/>Histone-Lysine N-Methyltransferase--antagonists & inhibitors<br/>Humans<br/>Molecular Dynamics Simulation<br/>Myeloid-Lymphoid Leukemia Protein--antagonists & inhibitors<br/>Protein Interaction Domains and Motifs--drug effects<br/>Protein Structure, Tertiary<br/>Proto-Oncogene Proteins--antagonists & inhibitors<br/>Small Molecule Libraries--chemistry<br/>Structure-Activity Relationship