TY - GEN AU - Scott,Gregory AU - Zetterberg,Henrik AU - Jolly,Amy AU - Cole,James H AU - De Simoni,Sara AU - Jenkins,Peter O AU - Feeney,Claire AU - Owen,David R AU - Lingford-Hughes,Anne AU - Howes,Oliver AU - Patel,Maneesh C AU - Goldstone,Anthony P AU - Gunn,Roger N AU - Blennow,Kaj AU - Matthews,Paul M AU - Sharp,David J TI - Minocycline reduces chronic microglial activation after brain trauma but increases neurodegeneration SN - 1460-2156 PY - 2019///0530 KW - Adult KW - Aged KW - Brain Injuries, Traumatic KW - complications KW - Cognition Disorders KW - diagnostic imaging KW - Cross-Sectional Studies KW - Female KW - Humans KW - Image Processing, Computer-Assisted KW - Longitudinal Studies KW - Magnetic Resonance Imaging KW - Male KW - Microglia KW - drug effects KW - Middle Aged KW - Minocycline KW - therapeutic use KW - Neurodegenerative Diseases KW - chemically induced KW - Neurofilament Proteins KW - metabolism KW - Neuropsychological Tests KW - Positron-Emission Tomography KW - Pyrimidines KW - pharmacokinetics KW - Statistics, Nonparametric KW - Young Adult N1 - Publication Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1093/brain/awx339 ER -