The delta opioid peptide D-Alanine 2, Leucine 5 Enkephaline (DADLE)-induces neuroprotection through cross-talk between the UPR and pro-survival MAPK-NGF-Bcl2 signaling pathways via modulation of several micro-RNAs in SH-SY5Y cells subjected to ER stress. [electronic resource]
- Cell biology international May 2018
- 543-569 p. digital
Publication Type: Journal Article
1095-8355
10.1002/cbin.10923 doi
Cell Line, Tumor Cell Survival--drug effects Dopaminergic Neurons--cytology Endoplasmic Reticulum Stress Enkephalin, Leucine-2-Alanine--pharmacology Humans MAP Kinase Signaling System MicroRNAs--metabolism Mitogen-Activated Protein Kinases--metabolism Nerve Growth Factor--metabolism Neuroprotective Agents--pharmacology Protein Aggregates Proto-Oncogene Proteins c-bcl-2--metabolism Unfolded Protein Response--drug effects