TY - GEN AU - Zhang,C AU - Kelkar,A AU - Nasirikenari,M AU - Lau,J T Y AU - Sveinsson,M AU - Sharma,U C AU - Pokharel,S AU - Neelamegham,S TI - The physical spacing between the von Willebrand factor D'D3 and A1 domains regulates platelet adhesion in vitro and in vivo SN - 1538-7836 PY - 2019///0906 KW - Animals KW - Blood Platelets KW - cytology KW - DNA, Complementary KW - metabolism KW - Female KW - HEK293 Cells KW - Hemostasis KW - Humans KW - Hydrodynamics KW - Male KW - Mice KW - Microfluidics KW - Mucins KW - chemistry KW - Phenotype KW - Platelet Activation KW - Platelet Adhesiveness KW - Platelet Function Tests KW - Protein Binding KW - Protein Domains KW - Protein Folding KW - Ristocetin KW - Shear Strength KW - Thrombocytopenia KW - blood KW - Thrombosis KW - von Willebrand Factor N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural UR - https://doi.org/10.1111/jth.13927 ER -