TY - GEN AU - Peter,B AU - Bibi,S AU - Eisenwort,G AU - Wingelhofer,B AU - Berger,D AU - Stefanzl,G AU - Blatt,K AU - Herrmann,H AU - Hadzijusufovic,E AU - Hoermann,G AU - Hoffmann,T AU - Schwaab,J AU - Jawhar,M AU - Willmann,M AU - Sperr,W R AU - Zuber,J AU - Sotlar,K AU - Horny,H-P AU - Moriggl,R AU - Reiter,A AU - Arock,M AU - Valent,P TI - Drug-induced inhibition of phosphorylation of STAT5 overrides drug resistance in neoplastic mast cells SN - 1476-5551 PY - 2019///0219 KW - Adult KW - Aged KW - Aged, 80 and over KW - Animals KW - Apoptosis KW - drug effects KW - Cell Cycle Checkpoints KW - Cell Line, Tumor KW - Dasatinib KW - pharmacology KW - Dogs KW - Drug Resistance, Neoplasm KW - Drug Synergism KW - Female KW - G2 Phase Cell Cycle Checkpoints KW - Humans KW - Leukemia, Mast-Cell KW - drug therapy KW - Male KW - Mast Cells KW - Mastocytosis, Systemic KW - Middle Aged KW - Norbornanes KW - Phosphorylation KW - Protein Kinase Inhibitors KW - Proto-Oncogene Proteins c-kit KW - metabolism KW - Pyrimidines KW - STAT5 Transcription Factor KW - Staurosporine KW - analogs & derivatives KW - Tumor Suppressor Proteins KW - Young Adult N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/leu.2017.338 ER -