TY  - GEN
AU  - Cooney,Jeffrey D
AU  - Lin,An-Ping
AU  - Jiang,Daifeng
AU  - Wang,Long
AU  - Suhasini,Avvaru N
AU  - Myers,Jamie
AU  - Qiu,ZhiJun
AU  - Wölfler,Albert
AU  - Sill,Heinz
AU  - Aguiar,Ricardo C T
TI  - Synergistic Targeting of the Regulatory and Catalytic Subunits of PI3Kδ in Mature B-cell Malignancies
SN  - 1557-3265
PY  - 2019///0911
KW  - Aminopyridines
KW  - pharmacology
KW  - Animals
KW  - Antineoplastic Combined Chemotherapy Protocols
KW  - B-Lymphocytes
KW  - metabolism
KW  - Benzamides
KW  - Catalytic Domain
KW  - drug effects
KW  - Cell Line, Tumor
KW  - Cell Survival
KW  - Class I Phosphatidylinositol 3-Kinases
KW  - antagonists & inhibitors
KW  - Cyclic Nucleotide Phosphodiesterases, Type 4
KW  - genetics
KW  - Cyclopropanes
KW  - Drug Repositioning
KW  - Drug Synergism
KW  - Humans
KW  - Leukemia, Lymphocytic, Chronic, B-Cell
KW  - drug therapy
KW  - Lymphoma, Large B-Cell, Diffuse
KW  - Mice
KW  - Mice, Nude
KW  - Phosphodiesterase 4 Inhibitors
KW  - Protein Kinase Inhibitors
KW  - Purines
KW  - Quinazolinones
KW  - Receptors, Antigen, B-Cell
KW  - Signal Transduction
KW  - Syk Kinase
KW  - Xenograft Model Antitumor Assays
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S
UR  - https://doi.org/10.1158/1078-0432.CCR-17-2218
ER  -