Cooney, Jeffrey D <br/><br/>
Synergistic Targeting of the Regulatory and Catalytic Subunits of PI3Kδ in Mature B-cell Malignancies.  [electronic resource] 

 -  Clinical cancer research : an official journal of the American Association for Cancer Research  03 2018 
 - 1103-1113 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S. 
<br/><br/><label>ISSN: </label>1557-3265 
<br/><br/><label>Standard No.: </label>10.1158/1078-0432.CCR-17-2218  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Aminopyridines--pharmacology<br/>Animals<br/>Antineoplastic Combined Chemotherapy Protocols--pharmacology<br/>B-Lymphocytes--metabolism<br/>Benzamides--pharmacology<br/>Catalytic Domain--drug effects<br/>Cell Line, Tumor<br/>Cell Survival--drug effects<br/>Class I Phosphatidylinositol 3-Kinases--antagonists & inhibitors<br/>Cyclic Nucleotide Phosphodiesterases, Type 4--genetics<br/>Cyclopropanes--pharmacology<br/>Drug Repositioning<br/>Drug Synergism<br/>Humans<br/>Leukemia, Lymphocytic, Chronic, B-Cell--drug therapy<br/>Lymphoma, Large B-Cell, Diffuse--drug therapy<br/>Mice<br/>Mice, Nude<br/>Phosphodiesterase 4 Inhibitors--pharmacology<br/>Protein Kinase Inhibitors--pharmacology<br/>Purines--pharmacology<br/>Quinazolinones--pharmacology<br/>Receptors, Antigen, B-Cell--metabolism<br/>Signal Transduction--drug effects<br/>Syk Kinase--metabolism<br/>Xenograft Model Antitumor Assays