TY - GEN AU - Lagares,David AU - Santos,Alba AU - Grasberger,Paula E AU - Liu,Fei AU - Probst,Clemens K AU - Rahimi,Rod A AU - Sakai,Norihiko AU - Kuehl,Tobias AU - Ryan,Jeremy AU - Bhola,Patrick AU - Montero,Joan AU - Kapoor,Mohit AU - Baron,Murray AU - Varelas,Xaralabos AU - Tschumperlin,Daniel J AU - Letai,Anthony AU - Tager,Andrew M TI - Targeted apoptosis of myofibroblasts with the BH3 mimetic ABT-263 reverses established fibrosis SN - 1946-6242 PY - 2018///0727 KW - Aniline Compounds KW - pharmacology KW - Animals KW - Apoptosis KW - drug effects KW - Biomechanical Phenomena KW - Cell Survival KW - Dermis KW - pathology KW - Disease Models, Animal KW - Extracellular Matrix KW - metabolism KW - Fibrosis KW - Humans KW - Male KW - Mechanotransduction, Cellular KW - Mice, Inbred C57BL KW - Mitochondria KW - Mitochondrial Membranes KW - Myofibroblasts KW - Scleroderma, Systemic KW - Signal Transduction KW - Sulfonamides KW - bcl-X Protein N1 - Publication Type: Journal Article UR - https://doi.org/10.1126/scitranslmed.aal3765 ER -