TY - GEN AU - Good,Miranda E AU - Chiu,Yu-Hsin AU - Poon,Ivan K H AU - Medina,Christopher B AU - Butcher,Joshua T AU - Mendu,Suresh K AU - DeLalio,Leon J AU - Lohman,Alexander W AU - Leitinger,Norbert AU - Barrett,Eugene AU - Lorenz,Ulrike M AU - Desai,Bimal N AU - Jaffe,Iris Z AU - Bayliss,Douglas A AU - Isakson,Brant E AU - Ravichandran,Kodi S TI - Pannexin 1 Channels as an Unexpected New Target of the Anti-Hypertensive Drug Spironolactone SN - 1524-4571 PY - 2019///0813 KW - Animals KW - Antihypertensive Agents KW - pharmacology KW - Arterioles KW - drug effects KW - Connexins KW - antagonists & inhibitors KW - Diuretics KW - HEK293 Cells KW - Humans KW - Hypertension KW - drug therapy KW - Jurkat Cells KW - Male KW - Mice KW - Mice, Inbred C57BL KW - Middle Aged KW - Mineralocorticoid Receptor Antagonists KW - Nerve Tissue Proteins KW - Spironolactone N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1161/CIRCRESAHA.117.312380 ER -