TY - GEN AU - Lis,Christian AU - Rubner,Stefan AU - Roatsch,Martin AU - Berg,Angela AU - Gilcrest,Tyler AU - Fu,Darwin AU - Nguyen,Elizabeth AU - Schmidt,Anne-Marie AU - Krautscheid,Harald AU - Meiler,Jens AU - Berg,Thorsten TI - Development of Erasin: a chromone-based STAT3 inhibitor which induces apoptosis in Erlotinib-resistant lung cancer cells SN - 2045-2322 PY - 2019///0812 KW - Antineoplastic Agents KW - pharmacology KW - Apoptosis KW - drug effects KW - Carcinoma, Non-Small-Cell Lung KW - drug therapy KW - Cell Line, Tumor KW - Chromones KW - Humans KW - Lung Neoplasms KW - Molecular Docking Simulation KW - Phosphorylation KW - Protein Processing, Post-Translational KW - STAT1 Transcription Factor KW - antagonists & inhibitors KW - STAT3 Transcription Factor KW - STAT5 Transcription Factor KW - Structure-Activity Relationship KW - Tumor Suppressor Proteins KW - src Homology Domains N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S UR - https://doi.org/10.1038/s41598-017-17600-x ER -