TY - GEN AU - Li,Xiaobo AU - Yang,Hongbao AU - Wu,Shenshen AU - Meng,Qingtao AU - Sun,Hao AU - Lu,Runze AU - Cui,Jian AU - Zheng,Yuxin AU - Chen,Wen AU - Zhang,Rong AU - Aschner,Michael AU - Chen,Rui TI - Suppression of PTPN6 exacerbates aluminum oxide nanoparticle-induced COPD-like lesions in mice through activation of STAT pathway SN - 1743-8977 PY - 2018///0827 KW - A549 Cells KW - Aluminum Oxide KW - toxicity KW - Animals KW - Apoptosis KW - drug effects KW - Apoptosis Regulatory Proteins KW - metabolism KW - Disease Progression KW - Dose-Response Relationship, Drug KW - Humans KW - Inflammation Mediators KW - Inhalation Exposure KW - adverse effects KW - Lung KW - Male KW - Metal Nanoparticles KW - Mice, Inbred C57BL KW - Phosphorylation KW - Pneumonia KW - chemically induced KW - Protein Tyrosine Phosphatase, Non-Receptor Type 6 KW - Pulmonary Disease, Chronic Obstructive KW - Pulmonary Emphysema KW - RNA-Binding Proteins KW - STAT3 Transcription Factor KW - Signal Transduction KW - Time Factors N1 - Publication Type: Journal Article UR - https://doi.org/10.1186/s12989-017-0234-0 ER -