Li, Xiaobo <br/><br/>
Suppression of PTPN6 exacerbates aluminum oxide nanoparticle-induced COPD-like lesions in mice through activation of STAT pathway.  [electronic resource] 

 -  Particle and fibre toxicology  Dec 2017 
 - 53 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1743-8977 
<br/><br/><label>Standard No.: </label>10.1186/s12989-017-0234-0  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>A549 Cells<br/>Aluminum Oxide--toxicity<br/>Animals<br/>Apoptosis--drug effects<br/>Apoptosis Regulatory Proteins--metabolism<br/>Disease Progression<br/>Dose-Response Relationship, Drug<br/>Humans<br/>Inflammation Mediators--metabolism<br/>Inhalation Exposure--adverse effects<br/>Lung--drug effects<br/>Male<br/>Metal Nanoparticles--toxicity<br/>Mice, Inbred C57BL<br/>Phosphorylation<br/>Pneumonia--chemically induced<br/>Protein Tyrosine Phosphatase, Non-Receptor Type 6--metabolism<br/>Pulmonary Disease, Chronic Obstructive--chemically induced<br/>Pulmonary Emphysema--chemically induced<br/>RNA-Binding Proteins--metabolism<br/>STAT3 Transcription Factor--metabolism<br/>Signal Transduction--drug effects<br/>Time Factors