TY  - GEN
AU  - Handley,Renee R
AU  - Reid,Suzanne J
AU  - Brauning,Rudiger
AU  - Maclean,Paul
AU  - Mears,Emily R
AU  - Fourie,Imche
AU  - Patassini,Stefano
AU  - Cooper,Garth J S
AU  - Rudiger,Skye R
AU  - McLaughlan,Clive J
AU  - Verma,Paul J
AU  - Gusella,James F
AU  - MacDonald,Marcy E
AU  - Waldvogel,Henry J
AU  - Bawden,C Simon
AU  - Faull,Richard L M
AU  - Snell,Russell G
TI  - Brain urea increase is an early Huntington's disease pathogenic event observed in a prodromal transgenic sheep model and HD cases
SN  - 1091-6490
PY  - 2018///0709
KW  - Adult
KW  - Animals
KW  - Animals, Genetically Modified
KW  - Corpus Striatum
KW  - metabolism
KW  - Disease Models, Animal
KW  - Female
KW  - Humans
KW  - Huntingtin Protein
KW  - genetics
KW  - Huntington Disease
KW  - Male
KW  - Sheep
KW  - Trinucleotide Repeat Expansion
KW  - Urea
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1073/pnas.1711243115
ER  -