Handley, Renee R <br/><br/>
Brain urea increase is an early Huntington's disease pathogenic event observed in a prodromal transgenic sheep model and HD cases.  [electronic resource] 

 -  Proceedings of the National Academy of Sciences of the United States of America  12 2017 
 - E11293-E11302 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1091-6490 
<br/><br/><label>Standard No.: </label>10.1073/pnas.1711243115  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Adult<br/>Animals<br/>Animals, Genetically Modified<br/>Corpus Striatum--metabolism<br/>Disease Models, Animal<br/>Female<br/>Humans<br/>Huntingtin Protein--genetics<br/>Huntington Disease--genetics<br/>Male<br/>Sheep<br/>Trinucleotide Repeat Expansion--genetics<br/>Urea--metabolism