TY  - GEN
AU  - Lessard,Samuel
AU  - Francioli,Laurent
AU  - Alfoldi,Jessica
AU  - Tardif,Jean-Claude
AU  - Ellinor,Patrick T
AU  - MacArthur,Daniel G
AU  - Lettre,Guillaume
AU  - Orkin,Stuart H
AU  - Canver,Matthew C
TI  - Human genetic variation alters CRISPR-Cas9 on- and off-targeting specificity at therapeutically implicated loci
SN  - 1091-6490
PY  - 2018///0709
KW  - CRISPR-Cas Systems
KW  - Genetic Loci
KW  - Genetic Therapy
KW  - Humans
KW  - Polymorphism, Single Nucleotide
KW  - RNA, Guide, CRISPR-Cas Systems
KW  - genetics
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1073/pnas.1714640114
ER  -