van Oosterwijk, Jolieke G

Hypoxia-induced upregulation of BMX kinase mediates therapeutic resistance in acute myeloid leukemia. [electronic resource] - The Journal of clinical investigation 01 2018 - 369-380 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1558-8238

10.1172/JCI91893 doi


Cell Hypoxia
Child
Child, Preschool
Drug Resistance, Neoplasm
Female
Gene Expression Regulation, Enzymologic
Gene Expression Regulation, Leukemic
Humans
Infant
Leukemia, Myeloid, Acute--genetics
Male
Protein-Tyrosine Kinases--biosynthesis
Signal Transduction
Sorafenib--pharmacology
Tumor Microenvironment
Up-Regulation
fms-Like Tyrosine Kinase 3--genetics