TY - GEN AU - Su,Yongwei AU - Li,Xinyu AU - Ma,Jun AU - Zhao,Jianyun AU - Liu,Shuang AU - Wang,Guan AU - Edwards,Holly AU - Taub,Jeffrey W AU - Lin,Hai AU - Ge,Yubin TI - Targeting PI3K, mTOR, ERK, and Bcl-2 signaling network shows superior antileukemic activity against AML ex vivo SN - 1873-2968 PY - 2018///1217 KW - Adolescent KW - Adult KW - Aged KW - Antineoplastic Agents KW - pharmacology KW - Cell Line, Tumor KW - Cell Survival KW - drug effects KW - Child KW - Child, Preschool KW - Drug Delivery Systems KW - Extracellular Signal-Regulated MAP Kinases KW - genetics KW - Female KW - Gene Expression Regulation KW - Humans KW - Leukemia, Myeloid, Acute KW - drug therapy KW - Male KW - Metabolic Networks and Pathways KW - Middle Aged KW - Phosphatidylinositol 3-Kinases KW - Proto-Oncogene Proteins c-bcl-2 KW - TOR Serine-Threonine Kinases KW - Up-Regulation KW - Young Adult N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/j.bcp.2017.11.022 ER -