TY  - GEN
AU  - Chang,Shih-Yu
AU  - Weber,Elijah J
AU  - Sidorenko,Viktoriya S
AU  - Chapron,Alenka
AU  - Yeung,Catherine K
AU  - Gao,Chunying
AU  - Mao,Qingcheng
AU  - Shen,Danny
AU  - Wang,Joanne
AU  - Rosenquist,Thomas A
AU  - Dickman,Kathleen G
AU  - Neumann,Thomas
AU  - Grollman,Arthur P
AU  - Kelly,Edward J
AU  - Himmelfarb,Jonathan
AU  - Eaton,David L
TI  - Human liver-kidney model elucidates the mechanisms of aristolochic acid nephrotoxicity
SN  - 2379-3708
PY  - 2019///0708
KW  - Animals
KW  - Aristolochic Acids
KW  - toxicity
KW  - Biomarkers
KW  - Biotransformation
KW  - Carcinogens
KW  - Dicumarol
KW  - metabolism
KW  - Epithelial Cells
KW  - Hepatocytes
KW  - drug effects
KW  - Humans
KW  - Kidney
KW  - Liver
KW  - Male
KW  - Multidrug Resistance-Associated Proteins
KW  - NAD(P)H Dehydrogenase (Quinone)
KW  - Nephrons
KW  - Pathology, Molecular
KW  - instrumentation
KW  - Rats
KW  - Rats, Sprague-Dawley
KW  - Renal Insufficiency, Chronic
KW  - Xenobiotics
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1172/jci.insight.95978
ER  -