TY  - GEN
AU  - Morishita,Ko
AU  - Shoji,Yoshimichi
AU  - Tanaka,Shunkichi
AU  - Fukui,Masaki
AU  - Ito,Yuma
AU  - Kitao,Tatsuya
AU  - Ozawa,Shin-Ichiro
AU  - Hirono,Shuichi
AU  - Shirahase,Hiroaki
TI  - Novel Non-carboxylate Benzoylsulfonamide-Based Protein Tyrosine Phosphatase 1B Inhibitors with Non-competitive Actions
SN  - 1347-5223
PY  - 2018///0110
KW  - Administration, Oral
KW  - Allosteric Regulation
KW  - drug effects
KW  - Amino Acid Sequence
KW  - Animals
KW  - Binding Sites
KW  - Blood Glucose
KW  - analysis
KW  - Dogs
KW  - Enzyme Inhibitors
KW  - chemistry
KW  - Hypoglycemic Agents
KW  - Inhibitory Concentration 50
KW  - Male
KW  - Mice
KW  - Mice, Obese
KW  - Molecular Dynamics Simulation
KW  - Protein Tyrosine Phosphatase, Non-Receptor Type 1
KW  - antagonists & inhibitors
KW  - Rats
KW  - Rats, Sprague-Dawley
KW  - Sequence Alignment
KW  - Structure-Activity Relationship
KW  - Sulfonamides
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1248/cpb.c17-00635
ER  -