TY  - GEN
AU  - Wilkinson,David J
AU  - Desilets,Antoine
AU  - Lin,Hua
AU  - Charlton,Sarah
AU  - Del Carmen Arques,Maria
AU  - Falconer,Adrian
AU  - Bullock,Craig
AU  - Hsu,Yu-Chen
AU  - Birchall,Kristian
AU  - Hawkins,Alastair
AU  - Thompson,Paul
AU  - Ferrell,William R
AU  - Lockhart,John
AU  - Plevin,Robin
AU  - Zhang,Yadan
AU  - Blain,Emma
AU  - Lin,Shu-Wha
AU  - Leduc,Richard
AU  - Milner,Jennifer M
AU  - Rowan,Andrew D
TI  - The serine proteinase hepsin is an activator of pro-matrix metalloproteinases: molecular mechanisms and implications for extracellular matrix turnover
SN  - 2045-2322
PY  - 2019///0705
KW  - Aggrecans
KW  - metabolism
KW  - Animals
KW  - Cartilage, Articular
KW  - cytology
KW  - Cattle
KW  - Cells, Cultured
KW  - Collagen
KW  - Extracellular Matrix
KW  - Humans
KW  - Matrix Metalloproteinase 1
KW  - chemistry
KW  - Matrix Metalloproteinase 3
KW  - Mice
KW  - Mice, Inbred C57BL
KW  - Molecular Dynamics Simulation
KW  - Osteoarthritis
KW  - Protein Structure, Tertiary
KW  - Receptor, PAR-2
KW  - Serine Endopeptidases
KW  - Synovitis
KW  - pathology
KW  - Tumor Necrosis Factor-alpha
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1038/s41598-017-17028-3
ER  -