Anticancer Properties of Halogenated Pyrrolo[3,2-d]pyrimidines with Decreased Toxicity via N5 Substitution. [electronic resource]
- ChemMedChem 01 2018
- 178-185 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1860-7187
10.1002/cmdc.201700641 doi
Animals Antineoplastic Agents--chemistry Cell Line, Tumor Cell Survival--drug effects DNA Damage Dose-Response Relationship, Drug Drug Screening Assays, Antitumor Halogenation Humans Maximum Tolerated Dose Mice Pyrimidines--chemistry Pyrroles--chemistry Structure-Activity Relationship