TY  - GEN
AU  - Holley,Rebecca J
AU  - Ellison,Stuart M
AU  - Fil,Daniel
AU  - O'Leary,Claire
AU  - McDermott,John
AU  - Senthivel,Nishanthi
AU  - Langford-Smith,Alexander W W
AU  - Wilkinson,Fiona L
AU  - D'Souza,Zelpha
AU  - Parker,Helen
AU  - Liao,Aiyin
AU  - Rowlston,Samuel
AU  - Gleitz,Hélène F E
AU  - Kan,Shih-Hsin
AU  - Dickson,Patricia I
AU  - Bigger,Brian W
TI  - Macrophage enzyme and reduced inflammation drive brain correction of mucopolysaccharidosis IIIB by stem cell gene therapy
SN  - 1460-2156
PY  - 2019///0325
KW  - Animals
KW  - Brain
KW  - enzymology
KW  - Cytokines
KW  - metabolism
KW  - Disease Models, Animal
KW  - Encephalitis
KW  - etiology
KW  - Female
KW  - Genetic Therapy
KW  - methods
KW  - Gliosis
KW  - therapy
KW  - Glycosaminoglycans
KW  - genetics
KW  - Humans
KW  - Liver
KW  - Macrophages
KW  - Male
KW  - Mice
KW  - Mice, Inbred C57BL
KW  - Mice, Transgenic
KW  - Mucopolysaccharidosis III
KW  - complications
KW  - Prednisolone
KW  - therapeutic use
KW  - Spleen
KW  - Stem Cells
KW  - physiology
KW  - Sulfatases
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1093/brain/awx311
ER  -