TY  - GEN
AU  - Taban,Ismail M
AU  - Elshihawy,Hosam E A E
AU  - Torun,Beyza
AU  - Zucchini,Benedetta
AU  - Williamson,Clare J
AU  - Altuwairigi,Dania
AU  - Ngu,Adeline S T
AU  - McLean,Kirsty J
AU  - Levy,Colin W
AU  - Sood,Sakshi
AU  - Marino,Leonardo B
AU  - Munro,Andrew W
AU  - de Carvalho,Luiz Pedro S
AU  - Simons,Claire
TI  - Novel Aryl Substituted Pyrazoles as Small Molecule Inhibitors of Cytochrome P450 CYP121A1: Synthesis and Antimycobacterial Evaluation
SN  - 1520-4804
PY  - 2019///0401
KW  - Antitubercular Agents
KW  - chemistry
KW  - Bacterial Proteins
KW  - antagonists & inhibitors
KW  - Binding Sites
KW  - Crystallography, X-Ray
KW  - Cytochrome P-450 Enzyme Inhibitors
KW  - chemical synthesis
KW  - Cytochrome P-450 Enzyme System
KW  - Drug Evaluation, Preclinical
KW  - methods
KW  - Microbial Sensitivity Tests
KW  - Molecular Docking Simulation
KW  - Mycobacterium tuberculosis
KW  - drug effects
KW  - Pyrazoles
KW  - Small Molecule Libraries
KW  - Spectrophotometry, Ultraviolet
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1021/acs.jmedchem.7b01562
ER  -