TY  - GEN
AU  - Itkonen,Matti K
AU  - Tornio,Aleksi
AU  - Filppula,Anne M
AU  - Neuvonen,Mikko
AU  - Neuvonen,Pertti J
AU  - Niemi,Mikko
AU  - Backman,Janne T
TI  - Clopidogrel but Not Prasugrel Significantly Inhibits the CYP2C8-Mediated Metabolism of Montelukast in Humans
SN  - 1532-6535
PY  - 2019///0826
KW  - Acetates
KW  - administration & dosage
KW  - Adult
KW  - Clopidogrel
KW  - Computer Simulation
KW  - Cross-Over Studies
KW  - Cyclopropanes
KW  - Cytochrome P-450 CYP2C8
KW  - genetics
KW  - Cytochrome P-450 CYP2C8 Inhibitors
KW  - Drug Interactions
KW  - Female
KW  - Healthy Volunteers
KW  - Humans
KW  - Inactivation, Metabolic
KW  - Leukotriene Antagonists
KW  - Male
KW  - Models, Biological
KW  - Oxidation-Reduction
KW  - Pharmacogenetics
KW  - Pharmacogenomic Variants
KW  - Platelet Aggregation Inhibitors
KW  - Prasugrel Hydrochloride
KW  - Quinolines
KW  - Risk Assessment
KW  - Substrate Specificity
KW  - Sulfides
KW  - Young Adult
N1  - Publication Type: Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1002/cpt.947
ER  -