Itkonen, Matti K
Clopidogrel but Not Prasugrel Significantly Inhibits the CYP2C8-Mediated Metabolism of Montelukast in Humans. [electronic resource]
- Clinical pharmacology and therapeutics 09 2018
- 495-504 p. digital
Publication Type: Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
ISSN: 1532-6535
Standard No.: 10.1002/cpt.947 doi
Subjects--Topical Terms: Acetates--administration & dosage Adult Clopidogrel--administration & dosage Computer Simulation Cross-Over Studies Cyclopropanes Cytochrome P-450 CYP2C8--genetics Cytochrome P-450 CYP2C8 Inhibitors--administration & dosage Drug Interactions Female Healthy Volunteers Humans Inactivation, Metabolic Leukotriene Antagonists--administration & dosage Male Models, Biological Oxidation-Reduction Pharmacogenetics Pharmacogenomic Variants Platelet Aggregation Inhibitors--administration & dosage Prasugrel Hydrochloride--administration & dosage Quinolines--administration & dosage Risk Assessment Substrate Specificity Sulfides Young Adult