Itkonen, Matti K

Clopidogrel but Not Prasugrel Significantly Inhibits the CYP2C8-Mediated Metabolism of Montelukast in Humans. [electronic resource] - Clinical pharmacology and therapeutics 09 2018 - 495-504 p. digital

Publication Type: Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

1532-6535

10.1002/cpt.947 doi


Acetates--administration & dosage
Adult
Clopidogrel--administration & dosage
Computer Simulation
Cross-Over Studies
Cyclopropanes
Cytochrome P-450 CYP2C8--genetics
Cytochrome P-450 CYP2C8 Inhibitors--administration & dosage
Drug Interactions
Female
Healthy Volunteers
Humans
Inactivation, Metabolic
Leukotriene Antagonists--administration & dosage
Male
Models, Biological
Oxidation-Reduction
Pharmacogenetics
Pharmacogenomic Variants
Platelet Aggregation Inhibitors--administration & dosage
Prasugrel Hydrochloride--administration & dosage
Quinolines--administration & dosage
Risk Assessment
Substrate Specificity
Sulfides
Young Adult