Prediction of metabolism-induced hepatotoxicity on three-dimensional hepatic cell culture and enzyme microarrays. [electronic resource]
- Archives of toxicology Mar 2018
- 1295-1310 p. digital
Publication Type: Journal Article
1432-0738
10.1007/s00204-017-2126-3 doi
Animals Carcinoma, Hepatocellular--pathology Cell Culture Techniques--methods Cell Line, Tumor Chemical and Drug Induced Liver Injury--etiology Enzymes--analysis High-Throughput Screening Assays--instrumentation Humans Inhibitory Concentration 50 Lab-On-A-Chip Devices Lethal Dose 50 Liver Neoplasms--pathology Miniaturization Protein Array Analysis--instrumentation Rats Sensitivity and Specificity Toxicity Tests--instrumentation