TY - GEN AU - Sethumadhavan,Shalini AU - Silva,Murillo AU - Philbrook,Phaethon AU - Nguyen,Thao AU - Hatfield,Stephen M AU - Ohta,Akio AU - Sitkovsky,Michail V TI - Hypoxia and hypoxia-inducible factor (HIF) downregulate antigen-presenting MHC class I molecules limiting tumor cell recognition by T cells SN - 1932-6203 PY - 2017///1206 KW - ATP Binding Cassette Transporter, Subfamily B, Member 2 KW - genetics KW - Antigen-Presenting Cells KW - immunology KW - Cell Hypoxia KW - Gene Expression Regulation, Neoplastic KW - Genes, MHC Class I KW - Humans KW - Hypoxia-Inducible Factor 1 KW - Kidney Neoplasms KW - Oxygen KW - metabolism KW - Proteasome Endopeptidase Complex KW - T-Lymphocytes KW - Transcriptional Activation KW - Tumor Microenvironment KW - Von Hippel-Lindau Tumor Suppressor Protein N1 - Publication Type: Journal Article UR - https://doi.org/10.1371/journal.pone.0187314 ER -