TY - GEN AU - Murray,Michael AU - Zhang,Wei V AU - Edwards,Robert J TI - Variation in the Response of Clozapine Biotransformation Pathways in Human Hepatic Microsomes to CYP1A2- and CYP3A4-selective Inhibitors SN - 1742-7843 PY - 2018///1001 KW - Antipsychotic Agents KW - metabolism KW - Biotransformation KW - Clozapine KW - analogs & derivatives KW - Cytochrome P-450 CYP1A2 KW - Cytochrome P-450 CYP1A2 Inhibitors KW - pharmacology KW - Cytochrome P-450 CYP3A KW - Cytochrome P-450 CYP3A Inhibitors KW - Drug Interactions KW - Fluvoxamine KW - Humans KW - Hydroxylation KW - Ketoconazole KW - Liver KW - cytology KW - Microsomes, Liver KW - drug effects KW - Oxidation-Reduction N1 - Publication Type: Journal Article UR - https://doi.org/10.1111/bcpt.12933 ER -