The IKK-related kinase TBK1 activates mTORC1 directly in response to growth factors and innate immune agonists. [electronic resource]
- The EMBO journal 01 2018
- 19-38 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1460-2075
10.15252/embj.201696164 doi
Animals Cell Nucleus--metabolism Cells, Cultured Cytosol--metabolism Humans Immunity, Innate--drug effects Intercellular Signaling Peptides and Proteins--pharmacology Interferon Regulatory Factor-3--genetics Macrophages--drug effects Mechanistic Target of Rapamycin Complex 1--genetics Mice Phosphorylation--drug effects Protein Serine-Threonine Kinases--genetics Protein Transport Signal Transduction--drug effects TOR Serine-Threonine Kinases--genetics