Fu, Chengzhang <br/><br/>
The natural product carolacton inhibits folate-dependent C1 metabolism by targeting FolD/MTHFD.  [electronic resource] 

 -  Nature communications  11 2017 
 - 1529 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>2041-1723 
<br/><br/><label>Standard No.: </label>10.1038/s41467-017-01671-5  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Aminohydrolases--metabolism<br/>Anti-Bacterial Agents--pharmacology<br/>Antineoplastic Agents--pharmacology<br/>Bacterial Proteins--metabolism<br/>Biofilms--drug effects<br/>Biological Products--pharmacology<br/>Cell Line, Tumor<br/>Crystallography, X-Ray<br/>Enzyme Assays<br/>Folic Acid--metabolism<br/>Formate-Tetrahydrofolate Ligase--metabolism<br/>Humans<br/>Inhibitory Concentration 50<br/>Macrolides--pharmacology<br/>Methylenetetrahydrofolate Dehydrogenase (NADP)--metabolism<br/>Microbial Sensitivity Tests<br/>Minor Histocompatibility Antigens--metabolism<br/>Mitochondria--metabolism<br/>Multienzyme Complexes--metabolism<br/>Multifunctional Enzymes--metabolism<br/>Myxococcales--metabolism<br/>Neoplasms--drug therapy<br/>Protein Binding