TY - GEN AU - Pazhang,Mohammad AU - Mardi,Narges AU - Mehrnejad,Faramarz AU - Chaparzadeh,Nader TI - The combinatorial effects of osmolytes and alcohols on the stability of pyrazinamidase: Methanol affects the enzyme stability through hydrophobic interactions and hydrogen bonds SN - 1879-0003 PY - 2018///0809 KW - Amidohydrolases KW - chemistry KW - Enzyme Stability KW - drug effects KW - Hydrogen Bonding KW - Hydrophobic and Hydrophilic Interactions KW - Methanol KW - pharmacology KW - Molecular Dynamics Simulation KW - Mycobacterium tuberculosis KW - enzymology KW - Osmosis KW - Protein Conformation KW - Solvents N1 - Publication Type: Journal Article UR - https://doi.org/10.1016/j.ijbiomac.2017.11.039 ER -