Determining a threshold sub-acute dose leading to minimal physiological alterations following prolonged exposure to the nerve agent VX in rats. [electronic resource]
- Archives of toxicology Feb 2018
- 873-892 p. digital
Publication Type: Journal Article
1432-0738
10.1007/s00204-017-2108-5 doi
Animals Biomarkers--blood Body Temperature Body Weight Brain--drug effects Carrier Proteins--metabolism Chemical Warfare Agents--toxicity Cholinesterase Inhibitors--toxicity Cholinesterases--blood Dose-Response Relationship, Drug Male Motor Activity Muscles--drug effects Nerve Agents--toxicity Organothiophosphorus Compounds--toxicity Rats Rats, Sprague-Dawley Receptor, Muscarinic M2--metabolism Receptors, GABA-A--metabolism Toxicity Tests, Chronic