Novel C-Terminal Heat Shock Protein 90 Inhibitors (KU711 and Ku757) Are Effective in Targeting Head and Neck Squamous Cell Carcinoma Cancer Stem cells. [electronic resource]
- Neoplasia (New York, N.Y.) Dec 2017
- 1003-1011 p. digital
Publication Type: Journal Article
1476-5586
10.1016/j.neo.2017.09.003 doi
Animals Antineoplastic Agents--pharmacology Biomarkers Carcinoma, Squamous Cell--drug therapy Cell Line, Tumor Cell Self Renewal--drug effects Cell Survival--drug effects Disease Models, Animal Drug Resistance, Neoplasm Gene Expression Regulation, Neoplastic HSP90 Heat-Shock Proteins--antagonists & inhibitors Head and Neck Neoplasms--drug therapy Humans Mice MicroRNAs--genetics Neoplastic Stem Cells--drug effects Protein Interaction Domains and Motifs--drug effects Signal Transduction Squamous Cell Carcinoma of Head and Neck Tumor Cells, Cultured Xenograft Model Antitumor Assays