TY - GEN AU - Tong,Zhixiang AU - Martyn,Keir AU - Yang,Andy AU - Yin,Xiaolei AU - Mead,Benjamin E AU - Joshi,Nitin AU - Sherman,Nicholas E AU - Langer,Robert S AU - Karp,Jeffrey M TI - Towards a defined ECM and small molecule based monolayer culture system for the expansion of mouse and human intestinal stem cells SN - 1878-5905 PY - 2018///0723 KW - Animals KW - Cell Culture Techniques KW - methods KW - Cell Proliferation KW - drug effects KW - Coated Materials, Biocompatible KW - pharmacology KW - Collagen KW - Collagen Type IV KW - Drug Combinations KW - Epithelial Cells KW - cytology KW - Extracellular Matrix KW - Green Fluorescent Proteins KW - metabolism KW - Humans KW - Intestines KW - Laminin KW - Mice, Inbred C57BL KW - Proteoglycans KW - Pyrazoles KW - Pyrimidines KW - Receptors, G-Protein-Coupled KW - Stem Cells N1 - Publication Type: Journal Article UR - https://doi.org/10.1016/j.biomaterials.2017.10.038 ER -