Glidden, Michael D <br/><br/>
Solution structure of an ultra-stable single-chain insulin analog connects protein dynamics to a novel mechanism of receptor binding.  [electronic resource] 

 -  The Journal of biological chemistry  01 2018 
 - 69-88 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1083-351X 
<br/><br/><label>Standard No.: </label>10.1074/jbc.M117.808667  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Amino Acid Sequence<br/>Animals<br/>Diabetes Mellitus, Experimental--drug therapy<br/>Humans<br/>Hypoglycemic Agents--chemistry<br/>Insulin--analogs & derivatives<br/>Models, Molecular<br/>Nuclear Magnetic Resonance, Biomolecular<br/>Protein Binding<br/>Protein Conformation<br/>Protein Denaturation<br/>Protein Engineering<br/>Protein Stability<br/>Rats<br/>Receptor, Insulin--metabolism<br/>Swine<br/>Thermodynamics