TY - GEN AU - Magvanjav,Oyunbileg AU - Gong,Yan AU - McDonough,Caitrin W AU - Chapman,Arlene B AU - Turner,Stephen T AU - Gums,John G AU - Bailey,Kent R AU - Boerwinkle,Eric AU - Beitelshees,Amber L AU - Tanaka,Toshihiro AU - Kubo,Michiaki AU - Pepine,Carl J AU - Cooper-DeHoff,Rhonda M AU - Johnson,Julie A TI - Genetic Variants Associated With Uncontrolled Blood Pressure on Thiazide Diuretic/β-Blocker Combination Therapy in the PEAR (Pharmacogenomic Evaluation of Antihypertensive Responses) and INVEST (International Verapamil-SR Trandolapril Study) Trials SN - 2047-9980 PY - 2018///0702 KW - Adolescent KW - Adrenergic beta-Antagonists KW - adverse effects KW - Adult KW - Aged KW - Aldehyde Dehydrogenase 1 Family KW - Angiotensin-Converting Enzyme Inhibitors KW - therapeutic use KW - Antihypertensive Agents KW - Atenolol KW - Blood Pressure KW - drug effects KW - Calcium Channel Blockers KW - Chi-Square Distribution KW - Drug Combinations KW - Drug Resistance KW - genetics KW - Female KW - Florida KW - Genome-Wide Association Study KW - Georgia KW - Humans KW - Hydrochlorothiazide KW - Hypertension KW - diagnosis KW - Indoles KW - Logistic Models KW - Male KW - Middle Aged KW - Multivariate Analysis KW - Odds Ratio KW - Pharmacogenetics KW - Pharmacogenomic Variants KW - Polymorphism, Single Nucleotide KW - Prospective Studies KW - Retinal Dehydrogenase KW - Risk Factors KW - Sodium Chloride Symporter Inhibitors KW - Treatment Outcome KW - Vasodilator Agents KW - Verapamil KW - Young Adult N1 - Publication Type: Journal Article; Multicenter Study; Randomized Controlled Trial UR - https://doi.org/10.1161/JAHA.117.006522 ER -