TY - GEN AU - Stacpoole,Peter W TI - Therapeutic Targeting of the Pyruvate Dehydrogenase Complex/Pyruvate Dehydrogenase Kinase (PDC/PDK) Axis in Cancer SN - 1460-2105 PY - 2017///1113 KW - Acetyl Coenzyme A KW - metabolism KW - Adenosine Triphosphate KW - biosynthesis KW - Biomimetics KW - Citric Acid Cycle KW - physiology KW - Dichloroacetic Acid KW - pharmacology KW - Energy Metabolism KW - Glycolysis KW - Humans KW - Isoenzymes KW - Mitochondria KW - NAD KW - Neoplasms KW - drug therapy KW - Oxidative Phosphorylation KW - Protein Serine-Threonine Kinases KW - Pyruvate Dehydrogenase Acetyl-Transferring Kinase KW - Pyruvate Dehydrogenase Complex KW - antagonists & inhibitors KW - Pyruvic Acid N1 - Publication Type: Journal Article; Review UR - https://doi.org/10.1093/jnci/djx071 ER -