The helicase domain of Polθ counteracts RPA to promote alt-NHEJ. [electronic resource]
- Nature structural & molecular biology Dec 2017
- 1116-1123 p. digital
Publication Type: Journal Article
1545-9985
10.1038/nsmb.3494 doi
Animals CRISPR-Cas Systems--genetics Catalytic Domain--genetics Cell Line DNA Breaks, Double-Stranded DNA End-Joining Repair--genetics DNA-Directed DNA Polymerase--genetics Embryonic Stem Cells--cytology Homologous Recombination--genetics Mice Mice, Inbred C57BL Mice, Knockout Replication Protein A--antagonists & inhibitors Structure-Activity Relationship Translocation, Genetic--genetics DNA Polymerase theta