TY  - GEN
AU  - Stuhlmiller,Timothy J
AU  - Zawistowski,Jon S
AU  - Chen,Xin
AU  - Sciaky,Noah
AU  - Angus,Steven P
AU  - Hicks,Sean T
AU  - Parry,Traci L
AU  - Huang,Wei
AU  - Beak,Ju Youn
AU  - Willis,Monte S
AU  - Johnson,Gary L
AU  - Jensen,Brian C
TI  - Kinome and Transcriptome Profiling Reveal Broad and Distinct Activities of Erlotinib, Sunitinib, and Sorafenib in the Mouse Heart and Suggest Cardiotoxicity From Combined Signal Transducer and Activator of Transcription and Epidermal Growth Factor Receptor Inhibition
SN  - 2047-9980
PY  - 2018///0611
KW  - Animals
KW  - Antineoplastic Agents
KW  - toxicity
KW  - Cardiotoxicity
KW  - Cells, Cultured
KW  - Dose-Response Relationship, Drug
KW  - Echocardiography
KW  - ErbB Receptors
KW  - antagonists & inhibitors
KW  - Erlotinib Hydrochloride
KW  - Fatty Acids
KW  - metabolism
KW  - Female
KW  - Gene Expression Profiling
KW  - Heart
KW  - diagnostic imaging
KW  - Heart Diseases
KW  - chemically induced
KW  - Indoles
KW  - Mice
KW  - Molecular Targeted Therapy
KW  - Myocardial Contraction
KW  - drug effects
KW  - Myocardium
KW  - enzymology
KW  - Myocytes, Cardiac
KW  - Niacinamide
KW  - analogs & derivatives
KW  - Oxidation-Reduction
KW  - Phenylurea Compounds
KW  - Protein Interaction Maps
KW  - Protein Kinase Inhibitors
KW  - Proteomics
KW  - Pyrroles
KW  - Rats, Sprague-Dawley
KW  - STAT3 Transcription Factor
KW  - Signal Transduction
KW  - Sorafenib
KW  - Sunitinib
KW  - Time Factors
N1  - Publication Type: Comparative Study; Journal Article
UR  - https://doi.org/10.1161/JAHA.117.006635
ER  -