TY  - GEN
AU  - Jüptner,M
AU  - Flachsbart,F
AU  - Caliebe,A
AU  - Lieb,W
AU  - Schreiber,S
AU  - Zeuner,R
AU  - Franke,A
AU  - Schröder,J O
TI  - Low copy numbers of complement C4 and homozygous deficiency of C4A may predispose to severe disease and earlier disease onset in patients with systemic lupus erythematosus
SN  - 1477-0962
PY  - 2018///0917
KW  - Adult
KW  - Aged
KW  - Case-Control Studies
KW  - Chi-Square Distribution
KW  - Complement C4a
KW  - deficiency
KW  - DNA Copy Number Variations
KW  - Drug Therapy, Combination
KW  - Female
KW  - Gene Deletion
KW  - Gene Dosage
KW  - Gene Frequency
KW  - Genetic Association Studies
KW  - Genetic Predisposition to Disease
KW  - Germany
KW  - HLA-DRB1 Chains
KW  - genetics
KW  - Homozygote
KW  - Humans
KW  - Immunosuppressive Agents
KW  - therapeutic use
KW  - Logistic Models
KW  - Lupus Erythematosus, Systemic
KW  - diagnosis
KW  - Male
KW  - Middle Aged
KW  - Odds Ratio
KW  - Phenotype
KW  - Polymorphism, Single Nucleotide
KW  - Prognosis
KW  - Risk Factors
KW  - Severity of Illness Index
KW  - Time Factors
KW  - Young Adult
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1177/0961203317735187
ER  -