Jüptner, M <br/><br/>
Low copy numbers of complement C4 and homozygous deficiency of C4A may predispose to severe disease and earlier disease onset in patients with systemic lupus erythematosus.  [electronic resource] 

 -  Lupus  Apr 2018 
 - 600-609 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1477-0962 
<br/><br/><label>Standard No.: </label>10.1177/0961203317735187  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Adult<br/>Aged<br/>Case-Control Studies<br/>Chi-Square Distribution<br/>Complement C4a--deficiency<br/>DNA Copy Number Variations<br/>Drug Therapy, Combination<br/>Female<br/>Gene Deletion<br/>Gene Dosage<br/>Gene Frequency<br/>Genetic Association Studies<br/>Genetic Predisposition to Disease<br/>Germany<br/>HLA-DRB1 Chains--genetics<br/>Homozygote<br/>Humans<br/>Immunosuppressive Agents--therapeutic use<br/>Logistic Models<br/>Lupus Erythematosus, Systemic--diagnosis<br/>Male<br/>Middle Aged<br/>Odds Ratio<br/>Phenotype<br/>Polymorphism, Single Nucleotide<br/>Prognosis<br/>Risk Factors<br/>Severity of Illness Index<br/>Time Factors<br/>Young Adult