TY - GEN AU - Perlenfein,Tyler J AU - Murphy,Regina M TI - A mechanistic model to predict effects of cathepsin B and cystatin C on β-amyloid aggregation and degradation SN - 1083-351X PY - 2018///1114 KW - Algorithms KW - Amino Acid Substitution KW - Amyloid beta-Peptides KW - chemistry KW - Cathepsin B KW - Cystatin C KW - Fluorescence Resonance Energy Transfer KW - Humans KW - Kinetics KW - Models, Molecular KW - Mutagenesis, Site-Directed KW - Mutation KW - Nerve Tissue Proteins KW - Osmolar Concentration KW - Peptide Fragments KW - Protein Aggregation, Pathological KW - metabolism KW - Protein Interaction Domains and Motifs KW - Proteolysis KW - Recombinant Proteins KW - Reproducibility of Results KW - Solubility N1 - Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Validation Study UR - https://doi.org/10.1074/jbc.M117.811448 ER -