TY  - GEN
AU  - Storer,R Ian
AU  - Pike,Andy
AU  - Swain,Nigel A
AU  - Alexandrou,Aristos J
AU  - Bechle,Bruce M
AU  - Blakemore,David C
AU  - Brown,Alan D
AU  - Castle,Neil A
AU  - Corbett,Matthew S
AU  - Flanagan,Neil J
AU  - Fengas,David
AU  - Johnson,M Scott
AU  - Jones,Lyn H
AU  - Marron,Brian E
AU  - Payne,C Elizabeth
AU  - Printzenhoff,David
AU  - Rawson,David J
AU  - Rose,Colin R
AU  - Ryckmans,Thomas
AU  - Sun,Jianmin
AU  - Theile,Jonathan W
AU  - Torella,Rubben
AU  - Tseng,Elaine
AU  - Warmus,Joseph S
TI  - Highly potent and selective Na
SN  - 1464-3405
PY  - 2017///1206
KW  - Animals
KW  - Binding Sites
KW  - Dogs
KW  - Half-Life
KW  - Hepatocytes
KW  - metabolism
KW  - Humans
KW  - Infusions, Intravenous
KW  - Inhibitory Concentration 50
KW  - Mice
KW  - Microsomes, Liver
KW  - Molecular Docking Simulation
KW  - NAV1.7 Voltage-Gated Sodium Channel
KW  - chemistry
KW  - Pain
KW  - drug therapy
KW  - Piperidines
KW  - Protein Binding
KW  - Protein Structure, Tertiary
KW  - Pyridines
KW  - Rats
KW  - Structure-Activity Relationship
KW  - Sulfonamides
KW  - Thiadiazoles
KW  - Voltage-Gated Sodium Channel Blockers
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1016/j.bmcl.2017.09.056
ER  -