TY - GEN AU - Qin,Sisi AU - Liu,Duan AU - Kohli,Manish AU - Wang,Liguo AU - Vedell,Peter T AU - Hillman,David W AU - Niu,Nifang AU - Yu,Jia AU - Weinshilboum,Richard M AU - Wang,Liewei TI - TSPYL Family Regulates CYP17A1 and CYP3A4 Expression: Potential Mechanism Contributing to Abiraterone Response in Metastatic Castration-Resistant Prostate Cancer SN - 1532-6535 PY - 2019///0705 KW - Abiraterone Acetate KW - pharmacology KW - Cell Cycle Proteins KW - drug effects KW - Cell Proliferation KW - Cytochrome P-450 CYP3A KW - Cytochrome P-450 Enzyme Inhibitors KW - DNA-Binding Proteins KW - Dehydroepiandrosterone KW - metabolism KW - Gene Expression Regulation KW - Gene Knockdown Techniques KW - Hep G2 Cells KW - Humans KW - Male KW - Neoplasm Metastasis KW - Nuclear Proteins KW - Proportional Hazards Models KW - Prostatic Neoplasms, Castration-Resistant KW - drug therapy KW - RNA, Messenger KW - Steroid 17-alpha-Hydroxylase KW - antagonists & inhibitors KW - Treatment Outcome N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S UR - https://doi.org/10.1002/cpt.907 ER -