TY  - GEN
AU  - Zhou,Wangda
AU  - Johnson,Trevor N
AU  - Bui,Khanh H
AU  - Cheung,S Y Amy
AU  - Li,Jianguo
AU  - Xu,Hongmei
AU  - Al-Huniti,Nidal
AU  - Zhou,Diansong
TI  - Predictive Performance of Physiologically Based Pharmacokinetic (PBPK) Modeling of Drugs Extensively Metabolized by Major Cytochrome P450s in Children
SN  - 1532-6535
PY  - 2019///0705
KW  - Acetates
KW  - metabolism
KW  - Analgesics, Opioid
KW  - Anti-Asthmatic Agents
KW  - Anti-Inflammatory Agents, Non-Steroidal
KW  - Antifungal Agents
KW  - Bronchodilator Agents
KW  - Child
KW  - Child, Preschool
KW  - Cyclopropanes
KW  - Cytochrome P-450 CYP1A2
KW  - Cytochrome P-450 CYP2C19
KW  - Cytochrome P-450 CYP2C8
KW  - Cytochrome P-450 CYP2C9
KW  - Cytochrome P-450 CYP2D6
KW  - Cytochrome P-450 CYP3A
KW  - Cytochrome P-450 Enzyme System
KW  - Diclofenac
KW  - Esomeprazole
KW  - Histamine H1 Antagonists, Non-Sedating
KW  - Humans
KW  - Infant
KW  - Infant, Newborn
KW  - Itraconazole
KW  - Lansoprazole
KW  - Loratadine
KW  - analogs & derivatives
KW  - Models, Biological
KW  - Ondansetron
KW  - Pharmaceutical Preparations
KW  - Pharmacokinetics
KW  - Proton Pump Inhibitors
KW  - Quinolines
KW  - Serotonin Antagonists
KW  - Sufentanil
KW  - Sulfides
KW  - Theophylline
KW  - Tramadol
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1002/cpt.905
ER  -