Zhou, Wangda <br/><br/>
Predictive Performance of Physiologically Based Pharmacokinetic (PBPK) Modeling of Drugs Extensively Metabolized by Major Cytochrome P450s in Children.  [electronic resource] 

 -  Clinical pharmacology and therapeutics  07 2018 
 - 188-200 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1532-6535 
<br/><br/><label>Standard No.: </label>10.1002/cpt.905  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Acetates--metabolism<br/>Analgesics, Opioid--metabolism<br/>Anti-Asthmatic Agents--metabolism<br/>Anti-Inflammatory Agents, Non-Steroidal--metabolism<br/>Antifungal Agents--metabolism<br/>Bronchodilator Agents--metabolism<br/>Child<br/>Child, Preschool<br/>Cyclopropanes<br/>Cytochrome P-450 CYP1A2--metabolism<br/>Cytochrome P-450 CYP2C19--metabolism<br/>Cytochrome P-450 CYP2C8--metabolism<br/>Cytochrome P-450 CYP2C9--metabolism<br/>Cytochrome P-450 CYP2D6--metabolism<br/>Cytochrome P-450 CYP3A--metabolism<br/>Cytochrome P-450 Enzyme System--metabolism<br/>Diclofenac--metabolism<br/>Esomeprazole--metabolism<br/>Histamine H1 Antagonists, Non-Sedating--metabolism<br/>Humans<br/>Infant<br/>Infant, Newborn<br/>Itraconazole--metabolism<br/>Lansoprazole--metabolism<br/>Loratadine--analogs & derivatives<br/>Models, Biological<br/>Ondansetron--metabolism<br/>Pharmaceutical Preparations--metabolism<br/>Pharmacokinetics<br/>Proton Pump Inhibitors--metabolism<br/>Quinolines--metabolism<br/>Serotonin Antagonists--metabolism<br/>Sufentanil--metabolism<br/>Sulfides<br/>Theophylline--metabolism<br/>Tramadol--metabolism